The opening of the cap is big enough for most warts.

However it can happen, that you have a wart that can not be completely enclosed. In that case you treat the wart in two or three sections, directly after each other with WartFreezer. It is important that you make sure all sections are roughly the same size.

The time to hold the cap on the wart is at least 10 seconds for each treatment. Even if there is some overlap.